说明书 
EVO视讯 EVO真人生命基因基于自主研发的EditX™基因编辑平台，采用优化升级的CRISPR/Cas9系统，设计科学的MYC基因敲除方案。顺利获得RNP法、瞬转质粒法或慢病毒法将CRISPR/Cas9编辑体系递送到DMS273细胞中，然后经过真核抗性标记筛选出阳性细胞池，再使用3D单细胞打印技术挑选单克隆细胞，最后顺利获得基因组测序验证，检测合格后对MYC基因敲除的DMS273细胞进行扩增和冻存。
| 货号 | EDC07672 |
|---|---|
| 产品名称 | MYC基因敲除DMS273细胞 |
| 物种 | 人 |
| 细胞 | DMS273 |
| Cellosaurus ID | CVCL_1176 |
| 消化时间 | / |
| 基因 | MYC |
| 传代比例 | 1:3~1:4 |
| 基因ID |
4609
|
| 摘要 |
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Transs involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
|
| 癌症类型 | Small Cell Lung Carcinoma |
| 细胞形态 | 贴壁生长 |
| 完全培养基 | DMEM+10% FBS |
| 冻存培养基 | 90% FBS+10% DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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